Definitely not on each page. In addition to being annoying, that’s overkill and dilutes the value of the acknowledgement.
Once at end of binder should be fine. But you can also have a signature line for a few isolated policies that you consider especially important and want to emphasize.
Personally, I think acknowledgements are a bit overrated, at least from a legal standpoint. A signature is rarely enough to persuade an inspector, judge or arbitrator that an employee actually read and understood a policy. Hope that helps. Glenn